Provider: Ingenta Connect
Database: Ingenta Connect
TY - ABST
AU - Valentini, V.
AU - Marazzi, F.
AU - Bossola, M.
AU - Miccichè, F.
AU - Nardone, L.
AU - Balducci, M.
AU - Dinapoli, N.
AU - Bonomo, P.
AU - Autorino, R.
AU - Silipigni, S.
AU - Giuliani, F.
AU - Tamanti, C.
AU - Mele, M. C.
AU - Martorana, G. E.
TI - Nutritional counselling and oral nutritional supplements in head and neck cancer patients undergoing chemoradiotherapy
JO - Journal of Human Nutrition & Dietetics
PY - 2012-06-01T00:00:00///
VL - 25
IS - 3
SP - 201
EP - 208
How to cite this article: Valentini V., Marazzi F., Bossola M., Miccichè F., Nardone L., Balducci M., Dinapoli N., Bonomo P., Autorino R., Silipigni S., Giuliani F., Tamanti C., Mele M.C. & Martorana G.E. (2012) Nutritional counselling
and oral nutritional supplements in head and neck cancer patients undergoing chemoradiotherapy. J Hum Nutr Diet.
25, 201–208 Abstract
Background: The role of
nutritional counselling (NC) with or without oral nutritional supplements (ONS) in patients receiving chemoradiotherapy (CRT) for head and neck cancer (HNC) still remains to be clearly defined, particularly with regard to CRT‐related toxicity.
Methods: Patients undergoing
CRT for HNC received NC by the dietitian within the first 4 days of radiotherapy and weekly for the course of radiotherapy (approximately 6 weeks). A weekly supply of oral nutrition supplements [1560 kJ (373 kcal) per 100 g] for up to 3 months was provided to
Results: Twenty‐one patients completed CRT. Mucositis G3 developed in seven (33.3%) patients, whereas mucositis G4 was absent. Dysphagia was present before the start of treatment in four patients. In the remaining 17 patients, dysphagia G3 developed during/at
the end of treatment in five cases. The percentage of patients interrupting anti‐neoplastic treatment for was 28% for ≥6 days, 28% for 3–5 days and 44% for 0–2 days. Mucositis G3 frequency was lower in patients with a baseline body mass index (BMI, kg m−2)
≥25 (two out of 12; 16.6%) than in patients with BMI <25 (five out of nine; 55.5%) (P = 0.161) and in patients with a baseline mid arm circumference >30 cm than in those with a mid arm circumference in the range 28.1–30 cm and <28 cm, and higher
in patients with a greater weight loss and a greater reduction of serum albumin and mid arm circumference.
Conclusions: Nutritional counselling and ONS are associated with relatively low CRT‐related toxicity and with mild deterioration of nutritional parameters.
UR - http://www.ingentaconnect.com/content/bsc/jhnd/2012/00000025/00000003/art00002
M3 - doi:10.1111/j.1365-277X.2011.01220.x
UR - http://dx.doi.org/10.1111/j.1365-277X.2011.01220.x