Low-glycaemic index sweetener-based beverages reduce 24-h glucose profiles in healthy adults

Authors: Henry, C. J. K.; Newens, K. J.; Lightowler, H. J.

Source: Journal of Human Nutrition & Dietetics, Volume 22, Number 1, February 2009 , pp. 77-80(4)

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Abstract:

Background:

Previous research has shown that substitution of high-glycaemic index (GI) bread for low-GI bread can favourably alter the 24-h glucose profile. Given the high beverage consumption in the UK, the present study aimed to evaluate the impact of consuming a beverage containing a low-GI, natural sweetener at mealtimes compared to a sucrose-based beverage, on the 24-h glucose profile. Methods:

In a randomized crossover design, six subjects (aged 41 ± 16 years; body mass index = 25.8 ± 4.1 kg m⁻²) were provided with a diet including low-GI or control (sucrose) beverages on two nonconsecutive days. On each study day, subjects consumed the low-GI or control beverage at breakfast, lunch and dinner. Interstitial glucose concentrations were measured over 24 h using a continuous glucose monitoring system. Results:

Compared to the control beverage, the low-GI beverage significantly reduced mean glucose concentration over 24 h (P < 0.05). Similarly, 24-h and daytime incremental area under the curves for glucose were significantly lower (P = 0.001). Conclusions:

The substitution of a sucrose-based beverage for a beverage containing a low-GI, natural sweetener at mealtimes is a simple dietary change that can significantly reduce 24-h glucose levels and may be beneficial for many individuals.

Keywords: continuous glucose monitoring; glycaemic index; glycaemic response

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1365-277X.2008.00930.x

Publication date: 2009-02-01