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Immune modulating nutrition support for a patient with severe toxic epidermal necrolysis

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Toxic epidermal necrolysis (TEN) is a rare but serious condition with a high mortality rate, whose clinical features resemble major thermal injury. Nutritional substrates which can affect the immune response have been shown to benefit burned and critically ill patients but there is a lack of data in the TEN literature. A case study is presented of a 63-year-old female admitted to our burn unit with extensive skin and mucosal involvement. Immune modulating artificial nutrition support was given initially via the parenteral route and then the nasogastric route. Maintenance of the patient's nutritional status and clinical outcome suggest that there may be a role for this type of intervention in TEN.

Keywords: arginine; burns; glutamine; nutrition support; omega 3 fatty acids; toxic epidermal necrolysis

Document Type: Case Report


Publication date: 2005-08-01

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