A Search for Obligatory Paternal Alleles in a DNA Database to Find an Alleged Rapist in a Fatherless Paternity Case

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Abstract:

Abstract:  A sexual assault case resulted in a pregnancy, which was subsequently aborted. The alleged father of the fetus was unknown. Maternal and fetal types were obtained using the 11‐locus AmpFlSTR® SGM Plus® kit. The national DNA database was searched for the paternal obligatory alleles and detected two suspects who could not be excluded as father of the male fetus. Additional typing using the AmpFlSTR® Minifiler kit, containing three additional autosomal loci, was not sufficient to exclude either suspect. Subsequent typing using the PowerPlex® 16, containing four additional loci, and Y‐Filer kits resulted in excluding one suspect. Searching a database for paternal obligatory alleles can be fruitful, but is fraught with possible false positive results so that finding a match must be taken as only preliminary evidence.

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1556-4029.2012.02095.x

Affiliations: 1: Forensic DNA and Biology Laboratory, Division of Identification and Forensic Science (DIFS), Israel Police National Headquarters, Jerusalem, Israel. 2: DNA Database Laboratory, Division of Identification and Forensic Science (DIFS), Israel Police National Headquarters, Jerusalem, Israel. 3: Department of Statistics and Department of Ecology, Evolution and Behavior, The Hebrew University of Jerusalem, Jerusalem, Israel.

Publication date: July 1, 2012

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