Abstract: Venous stasis predisposes to thrombosis. One hundred and sixty cases of fatal pulmonary thromboembolism were reviewed to determine how many cases had deep venous thromboses associated with venous blood flow reduction caused by external pressure from benign pelvic
masses. Three cases were identified, representing 2% of cases overall (3/160): a 44‐year‐old woman with a large uterine leiomyoma (1048 g); a 74‐year‐old man with prostatomegaly and bladder distension (containing 1 L of urine); and a 70‐year‐old
man with prostatomegaly and bladder distension (containing 3 L of urine). Although a rare cause of fatal deep venous thrombosis and pulmonary thromboembolism, space‐occupying pelvic lesions can lead to extrinsic pressure on adjacent veins reducing blood flow and causing stasis
and thrombosis. Individuals with large pelvic masses may, therefore, be at increased risk of pulmonary thromboembolism from deep venous thrombosis, particularly in the presence of concurrent risk factors such as immobility, thrombophilias, malignancy, and significant cardiopulmonary disease.