Skip to main content

The Role of Postmortem Cardiac Markers in the Diagnosis of Acute Myocardial Infarction

The full text article is not available.

At present, only title information is available on ingentaconnect.com for this article. This is due to copyright restrictions.

Abstract:

Abstract: 

Sudden cardiac deaths because of acute myocardial infarction (MI) constitute a significant percentage of the caseload for death investigators, coroners, and forensic pathologists. Clinicians use cardiac markers, highly sensitive and specific for myocardial damage, to screen living patients for acute MI; however, to this point, the utility of these markers in the autopsy setting has not been fully established. The current study included 10 decedents, five who died of acute MI, and five subjects who died of noncardiac disease. Samples of pericardial fluid and blood from multiple sites were tested for creatine kinase, creatinine kinase MB, and troponin-I. Three main conclusions were drawn: the levels of cardiac markers from all patients are significantly higher than the reference range for living patients, there are significant differences in cardiac marker levels between samples from different anatomic locations, and only three cardiac marker/anatomic site combinations were significantly different between the control and study groups.

Keywords: autopsy; cardiac markers; death; forensic pathology; forensic sciences; heart; myocardial infarction

Document Type: Research Article

DOI: https://doi.org/10.1111/j.1556-4029.2010.01368.x

Affiliations: 1: Medical University of South Carolina, Suite 309, 171 Ashley Avenue, PO Box 250908, Charleston, SC 29425. 2: Professional Pathology Services, Columbia, SC. 3: Fulton County Medical Examiner’s Office, Atlanta, GA.

Publication date: 2010-07-01

  • Access Key
  • Free ContentFree content
  • Partial Free ContentPartial Free content
  • New ContentNew content
  • Open Access ContentOpen access content
  • Partial Open Access ContentPartial Open access content
  • Subscribed ContentSubscribed content
  • Partial Subscribed ContentPartial Subscribed content
  • Free Trial ContentFree trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more