A Characterization of Sources of Isopropanol Detected on Postmortem Toxicologic Analysis

$48.00 plus tax (Refund Policy)

Download / Buy Article:



Isopropanol is an important chemical to forensic pathologists in that intoxication can result in death yet presence does not necessarily indicate intoxication. Several reports have been published, which indicate that isopropanol can be created endogenously in certain situations including diabetes mellitus, starvation, dehydration, and chronic ethanol use; however, a large-scale analysis addressing all of the possible causes of postmortem isopropanol detection has not been performed. A retrospective review of all cases examined at the Bexar County Medical Examiner’s Office between 1993 and 2008 in which isopropanol was detected in routine alcohol screening was undertaken. The cases were categorized by the source of the isopropanol, and the concentrations of isopropanol and acetone were analyzed. Analysis revealed isopropanol concentrations to be low (<100 mg/dL) in cases of antemortem and postmortem creation and in postmortem contamination and high (>100 mg/dL) in cases of antemortem exposure. These results are consistent with other published reports.

Keywords: acetone; decomposition; diabetes; forensic science; forensic toxicology; infection; isopropanol; postmortem

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1556-4029.2010.01386.x

Affiliations: Bexar County Medical Examiner’s Office, San Antonio, TX.

Publication date: July 1, 2010

Related content



Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more