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The effect of stimulation frequency on the transmural ventricular monophasic action potential in yellowfin tuna Thunnus albacares

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Monophasic action potentials (MAPs) were recorded from the spongy and compact layers of the yellowfin tuna Thunnus albacares ventricle as stimulation frequency was increased. MAP duration decreased with increase in stimulation frequency in both the spongy and compact myocardial layers, but no significant difference in MAP duration was observed between the layers.

Keywords: compact myocardium; endocardium; epicardium; heterogeneity; interval–duration relationship; spongy myocardium

Document Type: Research Article


Affiliations: 1: Faculty of Life Sciences, University of Manchester, 46 Grafton Street, Core Technology Facility, Manchester M13 9NT, U.K. 2: Institute of Membrane and Systems Biology, The University of Leeds, Leeds LS2 9JT, U.K. 3: Cooperative Marine Education and Research Program, NOAA Fisheries, Northeast Fisheries Science Center, Virginia Institute of Marine Science, P. O. Box 1346, Gloucester Point, VA 23062, U.S.A.

Publication date: 2011-02-01

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