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Early life stage toxicity of extracts from the African fish poison plants Tephrosia vogelii Hook. f. and Asystasia vogeliana Benth. on zebrafish embryos

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Embryos of Danio rerio are highly susceptible to extracts of the plants Tephrosia vogelii and Asystasia vogeliana. The concentration of the dried extracts at which 50% of the embryos were affected (EC50) after 24 h exposure were 320 and 572 μg l−1, respectively; corresponding 50% mortality (LC50) values after 48 h exposure were 493 and 869 μg l−1. Results indicate that the use of these ichthyotoxic plants might have a severe impact on the survival of fish larvae in the field.

Keywords: Asystasia vogeliana; Tephrosia vogelii; fish poison plants; toxicity; zebrafish

Document Type: Regular Paper


Affiliations: 1: Institute of Oceanography, University of Calabar, P.M.B. 1115, Calabar, Nigeria, 2: Department of Inland Fisheries, Leibniz-Institute of Freshwater Ecology and Inland Fisheries, M├╝ggelseedamm 310, 12587 Berlin, Germany and

Publication date: August 1, 2004


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