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Isolation of c‐myc genes from goldfish and their tissue specific expression

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One novel cellular myc gene (c‐myc), GM1, was isolated from a tetraploid cyprinid, the goldfish Carassius auratus. GM1 consisted of one non‐coding exon and two coding exons, presumably encoding a protein of 390 amino acid (aa) residues. The aa identity between GM1 and GM2, another c‐myc previously isolated from this species, was 88·8%. Quantitative RT‐PCR analysis revealed that GM1 was specifically expressed in liver and GM2 in ovary.

Keywords: c‐myc; expression; goldfish; quantitative RT‐PCR

Document Type: Regular Paper


Affiliations: 1: Department of Marine Sciences, University of Connecticut, Groton, CT 06340, U.S.A. and 2: Department of Aquatic Biosciences, Tokyo University of Fisheries, 4-5-7 Konan Minato-ku, Tokyo 108-8477, Japan

Publication date: 2003-11-01

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