Skip to main content

Organophosphosphate resistance-related mutations in the acetylcholinesterase gene of Tephritidae

Buy Article:

$51.00 plus tax (Refund Policy)

Abstract:

Abstract

Tephritid insects comprise one of the most devastating families of insect pests worldwide. Organophosphate insecticides have been extensively used for their control during the last 40 years. Inevitably, this has led to the development of resistance. Acetylcholinesterase is the principal target of organophosphates (OP) and, consequently, its gene is the most likely locus where resistance mutations appear. In this review, OP resistance-associated mutations in Tephritidae are described. Apart from the mutations that lie in the catalytic centre of the enzyme, those that lie at the C-terminal of the protein are of particular interest as they indicate a possible new mechanism of resistance. Nonetheless, the number of resistance-associated mutations in the catalytic centre of the Tephritidae ace gene is low, a fact that could be attributed to the fitness cost that any other mutations may have.

Keywords: ace; glycosyl-phosphatidyl-inositol; insecticide; tolerance

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1439-0418.2008.01373.x

Publication date: December 1, 2008

bsc/jen/2008/00000132/F0020009/art00012
dcterms_title,dcterms_description,pub_keyword
6
5
20
40
5

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more