IngentaConnect Fixed drug eruption from piroxicam

Authors: Cuerda Galindo, E¹; Goday Buján, JJ; García Silva, JM¹; Martínez, W¹; Verea Hernando, M¹; Fonseca, E¹

Source: Journal of the European Academy of Dermatology & Venereology, Volume 18, Number 5, September 2004 , pp. 586-587(2)

Publisher: Blackwell Publishing

Abstract:

The pathogenetic mechanism of fixed drug eruption (FDE) is still unknown. One of the most common causes of FDE is the use of nonsteroidal antiinflammatory drugs (NSAIDs). Oxicams are in the NSAID group and piroxicam is one of the most used of these drugs. FDE caused by piroxicam is rare but a few cases have been reported. Patch tests are useful for diagnosing some cases of FDE; they give variable results on previously affected skin while no reaction appears on unaffected skin. Some cases of cross-sensitivity among piroxicam and other substances have been reported. We report two new cases of FDE due to piroxicam with negative patch test on normal skin and positive results on affected skin.

Keywords: fixed drug eruption; piroxicam; patch test

Document Type: Research article

DOI: 10.1111/j.1468-3083.2004.00977.x

Affiliations: 1: Department of Dermatology, Hospital Juan Canalejo, C/Xubias de Arriba 84, 15006 A Coruña, Spain.

The full text electronic article is available for purchase. You will be able to download the full text electronic article after payment.

$54.87 plus tax