Nanostructured materials were designed to produce high-strength porous Y-TZP ceramics. Materials were prepared using homoaggregation resulting in a homogeneous distribution of nanosized particles attached to the surface of submicrometer-sized particles. After slip casting, green pellets were biscuit sintered at various temperatures in an ambient air atmosphere. The flexural strength of nanostructured ceramics substantially increased from 190 to 430 MPa in a narrow density range between 58% and 60% of theoretical density. This value is approximately two times higher than that obtained with dry-pressed biscuit-sintered Y-TZP ceramics exhibiting similar fractional density.