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Interconnected Hydroxyapatite Nanofibers in the Biomimetic Coating of a Bioinert Ceramic Substrate

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A bioinert ceramic substrate, α-Al2O3, has been coated with hydroxyapatite (HAp) by the biomimetic route using simulated body fluid (SBF) solution at room temperature. The substrate was incubated at 37°C in SBF for 6 days with a periodic replacement with freshly prepared SBF at 48-h intervals. After 6 days, continuous nanofiber-like structures of HAp (5–35 m in length, 0.05 m diameter) were obtained, connecting the intra- and interglobular clusters, within the coated mineral layer on the substrate surface. This is a unique and new observation, and this phenomenon has been demonstrated by a simple fractal growth model.

Document Type: Research Article


Affiliations: Bioceramics and Coating Division, Central Glass and Ceramic Research Institute, Kolkata 32, India

Publication date: November 1, 2007

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