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Point‐prevalence study of inappropriate antibiotic use at a tertiary Australian hospital

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Abstract:

Abstract

A point‐prevalence study at a tertiary Australian hospital found 199 of 462 inpatients (43%) to be receiving antibiotic therapy. Forty‐seven per cent of antibiotic use was discordant with guidelines or microbiological results and hence considered inappropriate. Risk factors for inappropriate antibiotic prescribing included bone/joint infections, the absence of infection, creatinine level >120 ┬Ámol/L, carbapenem or macrolide use and being under the care of the aged care/rehabilitation team. In the setting of finite antimicrobial stewardship resources, identification of local determinants for inappropriate antibiotic use may enable more targeted interventions.

Document Type: Research Article

DOI: http://dx.doi.org/10.1111/j.1445-5994.2012.02809.x

Affiliations: 1: Departments of Infectious Diseases and Microbiology 2: Pharmacy 3: Research, QEII Medical Centre, Perth, Western Australia, Australia

Publication date: June 1, 2012

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