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Intravenous zoledronic acid and oral alendronate in patients with a low trauma fracture: experience from an osteoporosis clinic

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Background/Aims: Oral bisphosphonates have been shown to be effective in treating osteoporosis. However, there has been a significant problem with compliance. Newer intravenous bisphosphonates are available for osteoporosis management, but have not been compared with oral bisphosphonates in a clinical setting. The aim of this study was to compare the safety and effectiveness of intravenous zoledronic acid (ZOL) and oral alendronate (ALN) in osteoporotic patients following a low trauma fracture.
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Keywords: alendronate; bisphosphonate; low trauma fracture; osteoporosis; treatment; zoledronic acid

Document Type: Research Article

Affiliations: 1: Graduate School of Medicine, The University of Wollongong, Wollongong, and 2: Institute of Rheumatology and Orthopaedics, Royal Prince Alfred Hospital, Sydney and

Publication date: 01 February 2011

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