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Fixed dose (555 MBq; 15 mCi) radioiodine for the treatment of hyperthyroidism: outcome and its predictors

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Radioiodine therapy (RIT) is an accepted treatment for hyperthyroidism and a 555-MBq (15-mCi) dose is frequently used. We aimed to assess treatment outcome with this dose, and to identify predictors of successful treatment. An analysis of 478 treated patients demonstrated an overall four-month cure rate of 79.5%; success rate was higher in patients with toxic multinodular goitre, solitary toxic adenoma, a smaller thyroid or less severe disease. This information may be of further assistance if variation in the dose of RIT is considered.

Keywords: 555 MBq; fixed dose; hyperthyroidism; radioiodine therapy; thyrotoxicosis; uptake ratio

Document Type: Research Article


Affiliations: 1: Endocrinology 2: Departments of Nuclear Medicine and PET

Publication date: 2010-12-01

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