Skip to main content

Cardiotoxicity with 5‐fluorouracil and capecitabine: more than just vasospastic angina

Buy Article:

$51.00 plus tax (Refund Policy)


In this case series we present a variety of different cardiac toxicities with 5‐fluorouracil and its pro‐drug capecitabine, including myocardial infarction, cardiomyopathy, sinoatrial and atrioventricular node dysfunction, tako‐tsubo cardiomyopathy and QT prolongation with torsade‐de pointes ventricular tachycardia. We stress the fact that while vasospasm is a well‐recognized side‐effect of this class of chemotherapeutic agent, broader cardiotoxicity is commonly seen and an increased awareness of the range of toxicity is necessary if repeat toxicity is to be avoided.

Keywords: capecitabine; cardiotoxicity; fluorouracil

Document Type: Research Article


Affiliations: Departments of Cardiology and

Publication date: April 1, 2010

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Partial Open Access Content
Partial Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
Cookie Policy
Ingenta Connect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more