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High‐risk febrile neutropenia in Auckland 2003–2004: the influence of the microbiology laboratory on patient treatment and the use of pathogen‐specific therapy

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Abstract:

Background: International guidelines recommend routine microbiological assessment of patients with febrile neutropenia, but do not recommend a change from broad‐spectrum antibiotic therapy to pathogen‐specific therapy when a clinically relevant organism has been isolated. The aim of the study was to determine the aetiology of febrile neutropenia in adult haematology patients at Auckland City Hospital, to document the changes in treatment made following isolation of a clinically relevant organism and to assess adverse outcomes in any patient who received pathogen‐specific therapy after a positive culture result.

Keywords: disease management; febrile neutropenia; hospital laboratory; pathogenā€specific therapy

Document Type: Research Article

DOI: https://doi.org/10.1111/j.1445-5994.2006.01239.x

Affiliations: Haematology Departments, Auckland City Hospital, Grafton, Auckland, New Zealand

Publication date: 2007-01-01

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