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Hyperprolactinaemia associated with a complex cystic pituitary mass: medical versus surgical therapy

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A 39‐year‐old woman presented with visual loss and hyperprolactinaemia. Magnetic resonance imaging showed an intrasellar and suprasellar mass with a large cystic component that was hyperintense on T2‐weighted imaging. Prolactin levels were up to 5400 mIU/L. Following trans‐sphenoidal surgery, histology showed ­elements of both a Rathke's cleft cyst and prolactinoma. We suggest primary surgical management of large cystic pituitary lesions with associated hyperprolactinaemia, particularly when there is hyperintensity on T2‐weighted imaging. (Intern Med J 2004; 34: 573−576)

Keywords: Rathke's cleft cyst; cabergoline; prolactinoma; trans‐­sphenoidal surgery

Document Type: Research Article


Affiliations: 1: Departments of Endocrinology and 2: Neurosurgery Christchurch Hospital, Christchurch, New Zealand

Publication date: 2004-09-01

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