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Acute renal failure following ingestion of wild mushrooms

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We describe three cases of acute renal failure in young men who ingested wild mushrooms with the intent of producing hallucinations. Two cases remained dialysis dependent and, in these cases, renal biopsy revealed tubulointerstitial nephritis and ¬≠fibrosis. Similar cases have been reported in other countries, but not in Australia. The most recognized mushroom nephrotoxin is orellanine, however the causative mushroom species and the actual toxin involved in these cases are unknown. (Intern Med J 2002; 32: 187−190)

Keywords: acute kidney failure; hallucinogens; mushroom poisoning; orellanine; ­interstitial nephritis

Document Type: Research Article


Affiliations: 1: Department of Nephrology, Austin & Repatriation Medical Centre, Heidelberg, 2: Department of Medicine, Bendigo Base Hospital, Bendigo 3: Department of Renal Pathology, Austin & Repatriation Medical Centre, Melbourne, 4: Department of Renal Pathology and 5: Department of Nephrology, Royal Melbourne Hospital, Melbourne, Victoria, Australia

Publication date: April 1, 2002


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