If you are experiencing problems downloading PDF or HTML fulltext, our helpdesk recommend clearing your browser cache and trying again. If you need help in clearing your cache, please click here . Still need help? Email help@ingentaconnect.com

Minidose (1 mg) warfarin as prophylaxis for central vein catheter thrombosis

$48.00 plus tax (Refund Policy)

Download / Buy Article:

Abstract:

Abstract

Background: Central vein catheters, which are used in the treatment of cancer patients, are prone to thrombotic complications of the catheter or adjacent vein. Previous studies suggest that 1 mg warfarin daily (minidose) can significantly reduce that risk.

Aims: This study aims to establish whether minidose warfarin could reduce catheter-related thrombosis in adult patients with haematological malignancies.

Methods: Patients were randomly selected to receive warfarin or not. The end-points studied were: (i) occlusion by thrombus, (ii) removal of catheter for other reasons or (iii) 90 days free of thrombus.

Results: There was no significant difference in the incidence of catheter thrombosis or venous thrombosis and no significant variation in catheter survival between the study and control groups.

Conclusions: This study found no benefit of the routine use of minidose warfarin for prophylaxis of central vein catheter thrombosis in patients with haematolog- ical malignancies and therefore does not support the routine use of minidose warfarin for prophylaxis in such patients. (Intern Med J 2002; 32: 84–88)

Keywords: central venous catheters; thrombosis; warfarin

Document Type: Research Article

DOI: http://dx.doi.org/10.1046/j.1445-5994.2002.00171.x

Affiliations: 1: Department of Haematology, Christchurch Hospital, and 2: Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand

Publication date: March 1, 2002

Related content

Tools

Favourites

Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more