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Acquired haemophilia in South Australia: a case series

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Abstract

Of eight cases of acquired haemophilia presenting over an 8-year period, six received immunosuppressive treatment, five with cyclophosphamide, vincristine and prednisolone (CVP). Five patients (four on immunosuppressive treatment) entered remission, two patients died and one was lost to follow up. Initially, the remissions were only partial. The median duration until partial remission was 10 weeks (range 1–55 weeks) and until complete remission was 35 weeks (range 2–59 weeks). Partial remission may proceed to complete remission without further chemotherapy. (Intern Med J 2001; 31: 556–559)
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Keywords: acquired haemophilia A; case series; partial remission; treatment

Document Type: Research Article

Affiliations: 1: Department of Haematology, Royal Adelaide Hospital, 2: Division of Haematology, Institute of Medical and Veterinary Science, and 3: Department of Haematology, Women’s and Children’s Hospital, Adelaide, South Australia, Australia

Publication date: 2001-12-01

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