Authors: LEE, Y-T¹; FUJITA, T.²; SHIMAMOTO, K.³; WU, Z.⁴; ZHU, J.⁵; CHUNG, N-s⁶; PARK, J-B⁷; LIAU, C-S⁸; CHEN, M-F⁸

Source: International Journal of Clinical Practice, Volume 60, Supplement 150, November 2006 , pp. 17-19(3)

Publisher: Wiley-Blackwell

Abstract:

Summary

Hypertensive patients with additional risk factors such as diabetes, hypercholesterolemia, left ventricular hypertrophy, and obesity require much more aggressive goals and powerful drug therapies than uncomplicated hypertensives. In addition, elderly hypertensive patients at high risk are most often predisposed to left ventricular dysfunction. To date no guidelines for the management of these patients are available in Asia. This article reviews the findings of the Chin-Shan Community Cardiovascular Cohort study, a longitudinal cohort study from Taiwan, which revealed that the incidence of cardiovascular events increases as the patient's hypertension becomes severe. The article suggests routine monitoring of microalbuminuria and a complete lipid profile on patients should be done in order to identify possible risk factors and the course of treatment.

Keywords: High-risk patients; metabolic syndrome; diabetes; hypertension; microalbuminuria; Asian population

Document Type: Research article

DOI: 10.1111/j.1742-1241.2006.01119.x

Affiliations: 1: National Taiwan University College of Medicine and University Hospital, Taipei; Min-Sheng General Hospital Tao-Yuan, Taiwan 2: Division of Nephrology and Endocrinology, University of Tokyo School of Medicine, Tokyo 3: 2nd Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan 4: Department of Epidemiology, An Zhen Hospital, Beijing 5: Department of Internal Medicine, Zhong Shan Hospital, Fu Dan University, Shanghai, China 6: Division of Cardiology, Yonsei Cardiovascular Center, Yonsei University College of Medicine, Seoul 7: Department of Medicine/Cardiology, Cheil General Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea 8: Department of Internal Medicine National Taiwan University Hospital, National Taiwan University College of Medicine, Taipei, Taiwan

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