Authors: SHAPERO, G.¹; DOWSON, A.²; LACOSTE, J.-P.³; ALMQVIST, P.⁴

Source: International Journal of Clinical Practice, Volume 60, Number 12, December 2006 , pp. 1530-1535(6)

Publisher: Wiley-Blackwell

Abstract:

Summary

The `Zomig Appropriate for Primary care' programme was developed to address the needs of primary care physicians (PCPs) to improve migraine management. As part of the programme, an international, open-label, 6-month clinical study was performed. The study included new and tangible outcome variables relevant to PCPs and recruited patients presenting in primary care with an established migraine diagnosis. Patients treated up to three migraine attacks per month with zolmitriptan orally disintegrating tablet (ODT) 2.5 mg. All other migraine attacks occurring during the study period were treated with the patient's usual migraine medication (including other triptans). Questionnaires were used to record patient treatment experiences at the study end. The primary end-point was the proportion of patients wanting to continue using zolmitriptan ODT. Some 595 patients treated 7171 migraine attacks with zolmitriptan ODT. Of the 504 patients who completed the 6-month questionnaire, 380 (75.4%) wished to continue using zolmitriptan ODT. The results of the study indicate that patient-orientated end-points are more motivational and meaningful to physicians than traditional end-points used in controlled clinical trials, allowing them to make informed decisions regarding migraine management.

Keywords: Migraine; primary care; zolmitriptan orally disintegrating tablet; Zomig Appropriate for Primary care

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1742-1241.2006.01208.x

Affiliations: 1: Markham Headache and Pain Treatment Centre, Markham, ON, Canada 2: The King's Headache Service, King's College Hospital, London, UK 3: Department of Internal Medicine, Hôpitaux de Paris, Paris, France 4: AstraZeneca R&D, Södertälje, Sweden

Publication date: 2006-12-01

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