In this study, the ability to form bone‐like apatite on surface of both pure natural hydroxapatite (N‐HA) and natural hydroxyapatite containing 5 wt% of ZrO2 or TiO2
or Al2O3, sintered at 1300°C for 2 h and soaked in the simulated body fluid for different times, was studied. It has been found that the presence of β‐tricalcium phosphate in N‐HA + 5 wt%
ZrO2 or TiO2 has promoted the precipitation of bone‐like apatite in the Zr or Ti poorest regions. By contrast, the presence of 5 wt% of Al2O3
did not induce any apatite precipitation on N‐HA sample surfaces.