Hemicrania Continua Evolving From Cluster Headache Responsive to Valproic Acid

Authors: Lambru, Giorgio; Castellini, Paola; Bini, Annamaria; Evangelista, Andrea; Manzoni, Gian Camillo; Torelli, Paola

Source: Headache: The Journal of Head and Face Pain, Volume 48, Number 9, October 2008 , pp. 1374-1376(3)

Publisher: Wiley-Blackwell

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Abstract:

Hemicrania continua (HC) is a rare type of primary headache characterized by a prompt and enduring response to indomethacin. We describe a patient who suffered from cluster headache evolving into ipsilateral HC, who does not tolerate a long-term indomethacin therapy. The case was complex in terms of diagnosis, associated comorbidity, and choice of treatment; after several trials with different therapeutic regimens, we started the patient on a therapy with valproic acid and obtained an improvement of her HC.

Keywords: hemicrania continua; cluster headache; valproic acid; indomethacin

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1526-4610.2008.01249.x

Publication date: 2008-10-01