Labetalol for Prophylactic Treatment of Intractable Migraine During Pregnancy

Authors: Dey, Ranjan; Khan, Sajid; Akhouri, Vimal; Wootton, Joshua; Bajwa, Zahid H.

Source: Headache: The Journal of Head and Face Pain, Volume 42, Number 7, July 2002 , pp. 642-645(4)

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Abstract:

Headaches tend to improve in the majority of migraineurs during pregnancy, but some patients report a worsening of migraine and present a management challenge because of the restrictions of pharmacotherapy during pregnancy. Treatment options become even more limited for pregnant migraineurs who develop preeclampsia. Labetalol was tried successfully in reducing the frequency, duration, and intensity of migraine attacks in a pregnant woman with preeclampsia. There were no significant side effects and the patient delivered a healthy baby without complications.

Keywords: migraine; prophylaxis; preeclampsia; Labetalol

Document Type: Research article

DOI: http://dx.doi.org/10.1046/j.1526-4610.2002.02152.x

Affiliations: 1: From the Arnold Pain Center, Department of Anesthesia and Critical Care, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

Publication date: 2002-07-01