Patients With Acenocoumarol Treatment and Migraine

The full text article is temporarily unavailable.

We apologise for the inconvenience. Please try again later.

Download / Buy Article:

Abstract:

Objective.–

The aim of our study was to investigate the possible effect of acenocoumarol, which is indicated for nonneurological disease, on headache.Background.–

It has been suggested that anticoagulation can have beneficial effects in the control of migraine attacks.Methods.–

Four hundred randomized patients on oral anticoagulant therapy were asked to complete a questionnaire regarding their headaches.Results.–

Headache was present before or during oral anticoagulation in 166 (66 migraineurs and 100 nonmigraineurs) of 326 respondents. The major finding was that oral anticoagulation produced improvement in 63% of patients with migraine versus 38% of patients with nonmigranous headache. Improvement was related to the severity of migraine but not to age.Conclusions.–

Oral anticoagulant therapy can improve migraine. The way in which anticoagulant therapy acts on migraine is unknown, but potential mechanisms include its effect on platelet aggregability and pharmacological effects such as suppression of enhanced nitric oxide.

Keywords: acenocoumarol; headache; migraine; prophylaxis

Document Type: Research Article

Publication date: January 1, 2000

Related content

Tools

Favourites

Share Content

Access Key

Free Content
Free content
New Content
New content
Open Access Content
Open access content
Subscribed Content
Subscribed content
Free Trial Content
Free trial content
Cookie Policy
X
Cookie Policy
ingentaconnect website makes use of cookies so as to keep track of data that you have filled in. I am Happy with this Find out more