Seizures in multiple sclerosis

Authors: Koch, Marcus; Uyttenboogaart, Maarten; Polman, Susan; De Keyser, Jacques

Source: Epilepsia, Volume 49, Number 6, June 2008 , pp. 948-953(6)

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Abstract:

Summary

Seizures have long been recognized to be part of the disease spectrum of multiple sclerosis (MS). While they occur in only a minority of patients with MS, epileptic seizures can have serious consequences. The treatment of MS can be epileptogenic, and antiepileptic treatment can conversely worsen the symptoms of MS. In this article we present an overview of the current literature on the epidemiology, clinical presentation, pathology, imaging, prognosis and treatment of epileptic seizures in MS.

Keywords: Multiple sclerosis; Seizure; Epilepsy; Convulsions; Treatment

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1528-1167.2008.01565.x

Affiliations: 1: Neurology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

Publication date: 2008-06-01