Thrombotic occlusion of the common carotid artery (CCA) in acute ischemic stroke treated with intravenous tissue plasminogen activator (TPA)

Authors: Sharma, V. K.; Tsivgoulis, G.; Lao, A. Y.; Flaster, M.; Frey, J. L.; Malkoff, M. D.; Alexandrov, A. V.

Source: European Journal of Neurology, Volume 14, Number 2, February 2007 , pp. 237-240(4)

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Abstract:

Although common carotid artery (CCA) occlusions are rare, acute clinical presentations vary from mild to devastating strokes primarily due to tandem occlusions in the intracranial arteries. Three patients with acute CCA occlusions were treated with systemic tissue plasminogen activator (TPA). Blood pressures were kept at the upper limits allowed with TPA therapy with fluid balance and the `head-down' position. Recanalization occurred in intracranial vessels only. Marked early neurological improvement occurred in two of three patients. CCA occlusions should not be considered contra-indication to systemic thrombolysis.

Keywords: Acute common carotid occlusion; cardioembolic; tandem lesions; thrombolysis

Document Type: Short communication

DOI: http://dx.doi.org/10.1111/j.1468-1331.2006.01654.x

Publication date: 2007-02-01