Hypoparathyroidism: A rare treatable cause of epilepsy - report of two cases

Authors: Bindu, M.¹; Harinarayana, C.V.²

Source: European Journal of Neurology, Volume 13, Number 7, July 2006 , pp. 786-788(3)

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Abstract:

Hypoparathyroidism occurs due to insufficient production of parathyroid hormone to maintain extracellular calcium levels within the normal range. The acute clinical symptoms and signs of hypoparathyroidism are those of hypocalcaemia, ranging from tingling and numbness of limb extremities to intractable seizures. Often seizures are mistaken for epilepsy. Though hypoparathyroidism is not uncommon, the diagnosis is often missed due to its unusual clinical manifestation. This is the first documented report with vitamin D, Parathormone levels and urinary biochemical parameters from India. We present two cases of hypoparathyroidism who presented with seizures along with a short review of literature.

Keywords: epilepsy; hypocalcemia; hypoparathyroidism; parathormone; vitamin D

Document Type: Short communication

DOI: http://dx.doi.org/10.1111/j.1468-1331.2006.01287.x

Affiliations: 1: Neurology and Department of Endocrinology 2: Metabolism, Sri Venkateswara Institute of Medical Science, Tirupati-517507, A.P, India

Publication date: 2006-07-01