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Identification of a new mouse Cd1d2 allele

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Abstract:

Summary

The mouse CD1 system is formed by two closely related genes named Cd1d1 and Cd1d2. Cd1d1 encodes a molecule that presents antigens to NKT cells. The function of the Cd1d2 gene has not been elucidated. Here we described a method to analyse variations in mouse Cd1 genes. We found a new allele for Cd1d2 characterized by a point mutation, resulting in a replacement of alanine at position 176 by a valine.

Document Type: Research Article

DOI: https://doi.org/10.1111/j.1365-2370.2004.00431.x

Publication date: 2004-02-01

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