Molecular analysis of HLA-DRB1 polymorphism in north-east Spain

Authors: Vidal S.; Morante M.P.; Moga E.; Mosquera A.M.; Querol S.; Garcia J.; Rodriguez-Sanchez J.L.

Source: European Journal of Immunogenetics, Volume 29, Number 1, February 2002 , pp. 75-77

Publisher: Wiley-Blackwell

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Abstract:

Summary

The DRB1* polymorphism in 941 randomly selected individuals from the Umbilical Cord Blood Bank of Barcelona (92.75% of Spanish origin) was determined by sequence-based typing. The HLA profile was similar to that of other Mediterranean populations, with DRB1*0701 and *0301 being the most frequent alleles. This may be a consequence of the mixture of alleles as a result of migration from contiguous geographical areas.

Language: English

Document Type: Research article

Publication date: 2002-02-01