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Dinucleotide repeat polymorphisms within the Flt-1 gene in minimal change nephropathy

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Dysregulation of Flt-1, a major receptor for vascular permeability factor (VPF), may provide a mechanism for the development of proteinuria in minimal change nephropathy (MCN). The gene for Flt-1 has a polymorphic dinucleotide repeat. We have demonstrated an 88% predominance of one allele and an 80% rate of homozygosity for this polymorphism with no association with MCN.
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Document Type: Research Article

Publication date: 1999-10-01

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