Part II: Recent Advances in Myocardial Contrast Echocardiography

Authors: Villanueva, Flordeliza S.; Porter, Thomas R.1; Xie, Feng1

Source: Echocardiography - Jnl Cardiovascular Ultrasound & Allied Techniques, Volume 19, Number 5, July 2002 , pp. 399-407(9)

Publisher: Blackwell Publishing

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Abstract:

Myocardial contrast enhancement following intravenous infusions or injections of perfluorocarbon-containing microbubbles has now been observed consistently in humans. Currently, the major challenge facing us is interpreting accurately what we see. The myocardial contrast patterns we observe have, thus far, been shown to detect myocardial perfusion abnormalities during dipyridamole, adenosine, and dobutamine stress echocardiography. They also have been shown to detect zones of no reflow following coronary revascularization in patients with acute myocardial infarction. These preliminary data will require validation in larger multicenter clinical studies.

(ECHOCARDIOGRAPHY, Volume 19, July 2002)

Keywords: ultrasound; microbubbles; perfluorocarbons; harmonics; intermittent imaging

Document Type: Research article

DOI: 10.1046/j.1540-8175.2002.00399.x

Affiliations: 1: University of Nebraska Medical Center, Omaha, Nebraska

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