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Psoriatic arthritis

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ABSTRACT

Psoriatic arthritis (PSA) is an entity of inflammatory joint disease associated with psoriasis. PSA belongs to the heterogeneous group of seronegative spondylarthropathies. Both peripheral joints and axial skeleton can be affected in a characteristic pattern. In addition to that, enthesitis and dactylitis are important extracutaneous manifestations. Uveitis anterior is temporarily seen in about one quarter of PSA patients. There is a closer relationship of nail and joint disease. This review provides data on drug and physical treatment options. In particular DMARDS and inhibitors of tumor necrosis factor α are established therapies with importance for quality of life and long term outcome. New drugs are tested in various trials.
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Keywords: DMARDS; biologics; dactylitis; enthesitis; psoriatic arthritis; treatment; uveitis

Document Type: Research Article

Affiliations: 1: Department of Rheumatology, 2: Centre for Physical Therapy and Rehabilitation, and 3: Department of Radiology, Hospital Dresden-Friedrichstadt, Academic Teaching Hospital of the Technical University of Dresden, Dresden, Germany

Publication date: 01 March 2010

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