Authors: NEUHAUS, ISAAC M.; ZANE, LEE T.; TOPE, WHITNEY D.

Source: Dermatologic Surgery, Volume 35, Number 6, June 2009 , pp. 920-928(9)

Publisher: Wiley-Blackwell

Abstract:

BACKGROUND

Erythematotelangiectatic (ET) rosacea is commonly treated with a variety of laser and light-based systems. Although many have been used successfully, there are a limited number of comparative efficacy studies. OBJECTIVE

To compare nonpurpuragenic pulsed dye laser (PDL) with intense pulsed light (IPL) treatment in the ability to reduce erythema, telangiectasia, and symptoms in patients with moderate facial ET rosacea. METHODS

Twenty-nine patients were enrolled in a randomized, controlled, single-blind, split-face trial with nonpurpuragenic treatment with PDL and IPL and untreated control. Three monthly treatment sessions were performed with initial PDL settings of 10-mm spot size, 7 J/cm², 6-ms pulse duration and cryogen cooling, and initial IPL settings of 560-nm filter, a pulse train of 2.4 and 6.0 ms in duration separated by a 15-ms delay, and a starting fluence of 25 J/cm². Evaluation measures included spectrophotometric erythema scores, blinded investigator grading, and patient assessment of severity and associated symptoms. RESULTS

PDL and IPL resulted in significant reduction in cutaneous erythema, telangiectasia, and patient-reported associated symptoms. No significant difference was noted between PDL and IPL treatment. CONCLUSION

A series of nonpurpuragenic PDL and IPL treatments in ET rosacea was performed with similar efficacy and safety, and both modalities seem to be reasonable choices for the treatment of ET rosacea.

The authors have indicated no significant interest with commercial supporters.

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1524-4725.2009.01156.x

Affiliations: 1: Department of Dermatology, University of California at San Francisco, San Francisco, California;

Publication date: 2009-06-01

Related content

• In this: publication
• By this: publisher
• In this Subject: Dermatology ,  Surgery
• By this author: NEUHAUS, ISAAC M. ;  ZANE, LEE T. ;  TOPE, WHITNEY D.

Website © Publishing Technology. Article copyright remains with the publisher, society or author(s) as specified within the article.

• Terms and conditions
• Privacy policy
• Information for advertisers