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Efficacy and Adverse Effects of Q-Switched Ruby Laser on Solar Lentigines: A Prospective Study of 91 Patients with Fitzpatrick Skin Type II, III, and IV

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Abstract:

BACKGROUND

Laser-induced postinflammatory hyperpigmentation could be a limiting factor for selecting patients appropriate for the use of ruby laser in the treatment of lentigenes, especially in dark-skinned individuals. OBJECTIVE

To evaluate the efficacy and adverse effects of Q-switched ruby laser light (694 nm) on solar lentigines in patients with Fitzpatrick skin type II, III, and IV. METHODS AND MATERIALS

Controlled comparison study in a university-based laser clinic center. Ninety-one solar lentigines in patients with skin type II, III, and IV were enrolled. All patients were followed for 6 months for frequency of side effects. Before-and-after photographs and images from all follow-up sessions were taken and then assessed by a blinded dermatologist for the evaluation of side effects. RESULTS

Complete clearance was achieved in all patients. Postinflammatory dyspigmentation occurred in 7.8% patients with Fitzpatrick skin type II, 9.8% patients with type III, and 16.6 patients with type IV (p=.67); all improved over a 6-month follow-up period. CONCLUSION

Q-switched ruby laser treatment is a safe procedure for the treatment of solar lentigines even in dark-skinned individuals. Considering routine factors in addition to melanin content alone is required for minimizing side effects, especially postinflammatory hyperpigmentation in darker skin.

The authors have indicated no significant interest with commercial supporters.

Document Type: Research Article

DOI: https://doi.org/10.1111/j.1524-4725.2008.34310.x

Affiliations: 1: Department of Dermatology, Imam Khumeini Hospital, Ilam University of Medical Science, Ilam, Iran; 2: Skin Research Center, Shohada-e Tajrish Hospital, Shaheed Beheshti Medical University, Tehran, Iran

Publication date: 2008-11-01

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