Diabetes, Obesity and Metabolism

Rising impact of Diabetes, Obesity and Metabolism
pp. 1-1(1)
Author: Donnelly, Richard

Islet adaptation to insulin resistance: mechanisms and implications for intervention
pp. 2-8(7)
Authors: Ahrén, B.; Pacini, G.

Obesity and diabetes as risk factors for coronary artery disease: from the epidemiological aspect to the initial vascular mechanisms
pp. 9-20(12)
Author: Sundell, J.

Reduction of body weight and co-morbidities by orlistat: The XXL – Primary Health Care Trial
pp. 21-27(7)
Author: Wirth, A.

Efficacy, dose–response relationship and safety of once-daily extended-release metformin (Glucophage^® XR) in type 2 diabetic patients with inadequate glycaemic control despite prior treatment with diet and exercise: results from two double-blind, placebo-controlled studies
pp. 28-39(12)
Authors: Fujioka, K.; Brazg, R. L.; Raz, I.; Bruce, S.; Joyal, S.; Swanink, R.; Pans, M.

Effects of agar (kanten) diet on obese patients with impaired glucose tolerance and type 2 diabetes
pp. 40-46(7)
Authors: Maeda, H.; Yamamoto, R.; Hirao, K.; Tochikubo, O.

Efficacy and safety comparative evaluation of orlistat and sibutramine treatment in hypertensive obese patients
pp. 47-55(9)
Authors: Derosa, G.; Cicero, A. F. G.; Murdolo, G.; Piccinni, M. N.; Fogari, E.; Bertone, G.; Ciccarelli, L.; Fogari, R.

Lower within-subject variability of fasting blood glucose and reduced weight gain with insulin detemir compared to NPH insulin in patients with type 2 diabetes
pp. 56-64(9)
Authors: Haak, T.; Tiengo, A.; Draeger, E.; Suntum, M.; Waldhäusl, W.

The anti-obesity effect of rimonabant is associated with an improved serum lipid profile
pp. 65-72(8)
Authors: Poirier, B.; Bidouard, J.-P.; Cadrouvele, C.; Marniquet, X.; Staels, B.; O'Connor, S. E.; Janiak, P.; Herbert, J.-M.

Insulin detemir used in basal-bolus therapy in people with type 1 diabetes is associated with a lower risk of nocturnal hypoglycaemia and less weight gain over 12 months in comparison to NPH insulin
pp. 73-82(10)
Authors: De Leeuw, I.; Vague, P.; Selam, J.-L.; Skeie, S.; Lang, H.; Draeger, E.; Elte, J. W. F.

Incidence of insulin resistance in obese subjects in a rural Japanese population: The Tanno and Sobetsu study
pp. 83-87(5)
Authors: Ohnishi, H.; Saitoh, S.; Takagi, S.; Ohata, J.; Takeuchi, H.; Isobe, T.; Katoh, N.; Chiba, Y.; Fujiwara, T.; Akasaka, H.; Shimamoto, K.

Efficacy and safety of ezetimibe co-administered with simvastatin in thiazolidinedione-treated type 2 diabetic patients
pp. 88-97(10)
Authors: Gaudiani, L. M.; Lewin, A.; Meneghini, L.; Perevozskaya, I.; Plotkin, D.; Mitchel, Y.; Shah, S.

Increased adiposity and reduced adipose tissue mRNA expression of uncoupling protein-2 in first-degree relatives of type 2 diabetic patients: evidence for insulin stimulation of UCP-2 and UCP-3 gene expression in adipose tissue
pp. 98-105(8)
Authors: Pedersen, S. B.; Nyholm, B.; Kristensen, K.; Nielsen, M. F.; Schmitz, O.; Richelsen, B.

Combination treatment of vitamin C and desferrioxamine suppresses glomerular superoxide and prostaglandin E₂ production in diabetic rats
pp. 106-109(4)
Authors: Iino, K.; Iwase, M.; Sonoki, K.; Yoshinari, M.; Iida, M.

News and Views
pp. 110-116(7)
Author: Holt, Richard I. G.