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The adiponectin gene SNP+45 is associated with coronary artery disease in Type 2 (non‐insulin‐dependent) diabetes mellitus

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Background  The ACRP30/adiponectin gene on chromosome 3q27, a region linked to the metabolic syndrome, encodes for the abundant adipocyte‐specific secreted protein. Consistent rodent and human studies suggested that this adipokine may be a molecular link between metabolic and cardiovascular diseases.
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Keywords: APM1 gene; Type 2 diabetes; adiponectin; case‐control study; coronary artery disease

Document Type: Research Article

Affiliations: 1: Genomics Medicine Department and the Hammersmith Genome Centre, Imperial College, London, UK 2: Institute of Biology-CNRS 8090, Pasteur Institute, Lille, France and 3: Division of Endocrinology, Lausanne University Hospital, Switzerland

Publication date: 01 July 2004

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