Doxycycline-induced pill esophagitis
Authors: Kadayifci A.; Gulsen M.T.; Koruk M.; Savas M.C.
Source: Diseases of the Esophagus, Volume 17, Number 2, June 2004 , pp. 168-171(4)
Publisher: Wiley-Blackwell
Abstract:
SUMMARY. Pill-induced esophagitis is a complication seen in patients who use certain medications such as tetracycline and non-steroidal anti-inflammatory drugs. In this short report, we described five cases of doxycycline-induced esophagitis with endoscopic images. All of the patients were young or middle-aged women. Dysphagia or odynophagia with retrosternal pain were the main presenting symptoms in all cases. The observed injuries were at the middle third of esophagus with a normal surrounding mucosa. All patients had a history of swallowing the capsule with a small amount of water or in a recumbent position. Two patients with dysphagia were managed by intravenous fluid support and parenteral acid suppression. The symptoms were improved in 27 days after the ceasing of the drug and control endoscopies were completely normal in all cases after 34 weeks of admission. The drug-induced esophagitis is not rare with certain drugs and should be suspected in all patients presenting with chest pain and dysphagia. Physicians must warn the patients to take the pills and capsules with enough liquid and in the upright position.Keywords: doxycycline; esophagitis; pill; ulcer
Document Type: Research article
DOI: http://dx.doi.org/10.1111/j.1442-2050.2004.00384.x
Affiliations: 1: Department of Gastroenterology, Faculty of Medicine, University of Gaziantep, Gaziantep, Turkey
Publication date: 2004-06-01
- In this: publication
- By this: publisher
- In this Subject: Gastroenterology
- By this author: Kadayifci A. ; Gulsen M.T. ; Koruk M. ; Savas M.C.

Shopping cart
Receive new issue alert
Get Permissions