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Marked atrophy of the right lobe seen in idiopathic portal hypertension confirmed by laparoscopy

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Abstract:

A 70-year-old-male was hospitalized for the treatment of esophageal varices and close examination of the liver. Blood chemistry tests revealed mild liver dysfunction. Abdominal ultrasound and computed tomography scan revealed marked atrophy of the right and quadrate lobes of the liver without abnormalities of the biliary system. Abdominal angiography revealed marked atrophy of the right lobe of the liver, without obliteration in the portal venous system, but it could not be determined whether the atrophy was congenital or secondary. Subsequently performed laparoscopy revealed marked atrophy of the anterior segment of the right lobe and quadrate lobe with the whitish scarred edge demarcating the border between the edge and neighboring liver parenchyma. The liver surface appeared to be undulant, but non-cirrhotic. These findings suggest secondary lobar atrophy of the liver, without cirrhosis. Liver biopsy of the left lobe showed the findings to be compatible with idiopathic portal hypertension (IPH), and we diagnosed IPH based on these findings and hepatic lobar atrophy was attributable to IPH. There have been few reports of cases with hepatic lobar atrophy associated with IPH, and the mechanism of atrophy is unclear. We report a case of IPH with marked liver atrophy in which laparoscopy is a decisive means whether liver atrophy is congenital or secondary.

Keywords: hepatic lobar atrophy; idiopathic portal hypertension; laparoscopy

Document Type: Research Article

DOI: http://dx.doi.org/10.1046/j.1443-1661.2002.00170.x

Affiliations: 1: The Department of Gastroenterology, Dokkyo University School of Medicine and 2: SHARP corporation Audio–Visual Systems Group, Tochigi, Japan

Publication date: April 1, 2002

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