IngentaConnect Early recovery from post-traumatic acute respiratory distress syn...

Authors: Reske, Andreas; Seiwerts, Matthias¹; Reske, Alexander²; Gottschaldt, Udo³; Schreiter, Dierk²

Source: Clinical Physiology and Functional Imaging, Volume 26, Number 6, November 2006 , pp. 376-379(4)

Abstract:

Summary Background

To present and discuss the rationale and possible benefits of timely alveolar recruitment in early post-traumatic acute respiratory distress syndrome. Methods

A 17-year-old patient who had sustained blunt thoracic trauma presented with severe hypoxaemia on admission and whole body computed tomography showed pulmonary contusion and substantial bilateral atelectasis. Oxygenation and lung mechanics did not improve with low tidal volume ventilation using high positive end-expiratory pressures (PEEPs). Therefore we applied an alveolar recruitment manoeuvre 7 h after admission. After alveolar recruitment, PEEP was titrated to the lowest level which prevented alveolar derecruitment. Results

Oxygenation and lung compliance improved rapidly and aeration of the entire lung was confirmed by computed tomography 27 h after the recruitment manoeuvre. The patient recovered completely and was discharged after 17 days. Conclusion

Although robust evidence is still lacking, several lines of evidence suggest potential benefits of timely alveolar recruitment. Patients with early post-traumatic respiratory failure seem to most readily respond to alveolar recruitment manoeuvres and could thus benefit from the gain in functional lung volume and oxygenation. Moreover the probability of ventilator associated complications may be reduced.

Keywords: acute respiratory distress syndrome; atelectasis; positive pressure respiration; thoracic injuries

Document Type: Research article

DOI: 10.1111/j.1475-097X.2006.00702.x

Affiliations: 1: Department of Diagnostic Radiology 2: Surgical Intensive Care Unit, University Hospital Leipzig, Leipzig, Germany 3: Department of Anaesthesiology and Intensive Care Medicine

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Early recovery from post-traumatic acute respiratory distress syndrome