IngentaConnect Head-shaking nystagmus in patients with a vestibular schwannoma

Authors: Humphriss R.L.¹; Baguley D.M.¹; Moffat D.A.²

Source: Clinical Otolaryngology & Allied Sciences, Volume 28, Number 6, December 2003 , pp. 514-519(6)

Abstract:

humphriss r.l.,baguley d.m. &moffat d.a.

(2003) Clin. Otolaryngol.28, 514–519 Head-shaking nystagmus in patients with a vestibular schwannoma

The aim of this study was to calculate the sensitivity of the head-shake test for peripheral and central vestibular dysfunction associated with unilateral sporadic vestibular schwannoma and to discuss the feasibility of using the head-shake test as a screening test. The study group consisted of 102 patients with unilateral sporadic vestibular schwannomas, who were seen consecutively for preoperative vestibular assessment, including the head-shake test. The sensitivity of the head-shake test for vestibular schwannoma was found to be 22%, and the sensitivity and specificity of the head-shake test for canal paresis (

25%) were found to be 27% and 88%, respectively. Patients with abnormalities in the central vestibular system and with a greater canal paresis were more likely to have head-shake nystagmus, although, even for severe canal paresis, the sensitivity of the test remained low at 36%. The direction of nystagmus was found to be contra-lateral to the side of the tumour in 86% of patients. It was concluded that the head-shake test is of insufficient sensitivity to be used as a screening test either for vestibular schwannoma or for vestibular-system abnormalities associated with vestibular schwannoma. The deduction is made that the head-shake test is of insufficient sensitivity or specificity to be of clinical value as a screening test for vestibular dysfunction in a general population with symptoms of imbalance.

Keywords: vestibular schwannoma; acoustic neuroma; head-shake nystagmus

Document Type: Research article

DOI: 10.1046/j.1365-2273.2003.00753.x

Affiliations: 1: Audiology (Box 94) and 2: Otolaryngology, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK