Long-term outcome of neonatal hyperbilirubinaemia: subjective and objective audiological measures

Authors: Öün B.¹; erbetçiolu B.¹; Duman N.²; Özkan H.²; Krkm G.¹

Source: Clinical Otolaryngology & Allied Sciences, Volume 28, Number 6, December 2003 , pp. 507-513(7)

Publisher: Wiley-Blackwell

Abstract:

öün b.,erbetçiolu b.,duman n.,özkan h.&krkm g.

(2003) Clin. Otolaryngol.28, 507–513 Long-term outcome of neonatal hyperbilirubinaemia: subjective and objective audiological measures

Neonatal hyperbilirubinaemia is a common cause of early onset sensorineural hearing loss. There is no exact method to detect the extent of the neurotoxicity of bilirubin. On the other hand, the auditory pathway is known to be one of the most sensitive parts of the central nervous system (CNS) to this toxic agent. This prospective follow-up study was performed to evaluate and compare the factors related to the hearing of neonates with severe hyperbilirubinaemia and an age-matched control group. Both of these groups were tested using auditory brainstem response (ABR) as well as evoked otoacoustic emissions. Additionally, both of these groups of children were evaluated subjectively using an early speech-language-communication evaluation questionnaire. There was no significant difference in either objective (ABR and evoked otoacoustic emission) or subjective assessment (questionnaire) between the study and control groups. Furthermore, no correlation between serum total bilirubin levels and ABR latencies or thresholds was found within the study group.

Keywords: hyperbilirubinaemia; neonatal; bilirubin toxicity/otoacoustic emissions/evoked potentials; auditory; brainstem/speech perception

Document Type: Research article

DOI: http://dx.doi.org/10.1046/j.1365-2273.2003.00752.x

Affiliations: 1: Otorhinolaryngology, Hearing, Balance and Speech Section and 2: Paediatrics, Dokuz Eylül University, Medical School, zmir, Turkeyzmir, Turkey">

Publication date: 2003-12-01

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