Human metapneumovirus infection among children in Taiwan: a comparison of clinical manifestations with other virus-associated respiratory tract infections

Authors: Wang, S.-M.; Liu, C.-C.¹; Wang, H.-C.²; Su, I.-J.²; Wang, J.-R.

Source: Clinical Microbiology & Infection, Volume 12, Number 12, December 2006 , pp. 1221-1224(4)

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Abstract:

This study compared the clinical, laboratory and radiological features of infections caused by human metapneumovirus (hMPV) with other respiratory viruses. Nasopharyngeal aspirates and throat swabs were obtained from children during a 9-week period. hMPV was the virus isolated most frequently, followed by adenovirus, influenza virus A, respiratory syncytial virus and influenza virus B. hMPV-infected children were younger, and were more likely to be female, to present with feeding difficulties, a rash, tachycardia and a longer duration of fever, and to cough less frequently. Increasing interstitial infiltrates and hyperinflation were the most common radiological findings. None of the children required mechanical ventilation.

Keywords: Bronchopneumonia; children; human metapneumovirus; respiratory tract infection; Taiwan

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.1469-0691.2006.01540.x

Affiliations: 1: Department of Pediatrics, National Cheng Kung University & Hospital 2: Division of Clinical Research, National Health Research Institutes

Publication date: 2006-12-01