Subcutaneous ventricular catheter reservoir and ventriculoperitoneal drain-related infections in preterm infants and young children
Methods By means of a retrospective chart analysis, the number of shunt infections and related risk factors were analyzed.
Results Twenty-one patients (30%) developed one or more infections, with an infection rate of 15.2% per surgical event. For an implanted reservoir or drain, the infection rates were 15.9 and 16.4%, respectively. The study group consisted of 39 (55.7%) preterm infants (<37 weeks) and 31 (44.3%) full-term infants (37 weeks), with infection rates of 33.3 and 25.8%, respectively. At the first surgical intervention 28 patients (40%) had a postmenstrual age less than 37 weeks, with an infection rate of 46.4%. At the time of surgery, 69.7% of the patients were aged less than 6 months, with an infection rate of 19.6%. The most frequent causative microorganism of the shunt infections was Staphylococcus epidermidis (42.1%).
Conclusions Prematurity is an important risk factor for ventricular catheter reservoir and ventriculoperitoneal drain-related infections, especially for patients with a postmenstrual age of less than 37 weeks at their initial shunt placement and extreme low birth weight infants have a high risk for infection. In our opinion the use of adequate antibiotic prophylaxis and optimal infection control measures are necessary to keep the rate of infection as low as possible.
Document Type: Research Article
Affiliations: 1: Department of Medical Microbiology, 2: Department of Neurosurgery, 3: Department of Neurology and 4: Department of Pediatrics, University Hospital Maastricht, Maastricht, The Netherlands
Publication date: 01 April 2000