Aleukaemic leukaemia cutis: case report and review of the literature

Authors: Wilkins R.; Janes S.

Source: Clinical & Laboratory Haematology, Volume 26, Number 1, February 2004 , pp. 73-75(3)

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Abstract:

Summary

‘Aleukaemic leukaemia cutis’ or acute leukaemia confined to the skin is extremely rare, although skin involvement with underlying leukaemia is well recognized, and is associated with a poor prognosis. We report a case of isolated acute myeloid leukaemia (AML) in the skin. A literature review shows this to be commonly misdiagnosed. Its recognition is important, because early diagnosis should lead to more appropriate chemotherapy, and a better prognosis. These patients probably require therapy directed specifically to the skin, as well as to other extramedullary sites, such as the central nervous system, to prevent early relapse.

Keywords: Acute myeloid leukaemia; cutaneous

Document Type: Research article

DOI: http://dx.doi.org/10.1111/j.0141-9854.2003.00582.x

Publication date: 2004-02-01