Concomitant angioimmunoblastic T-cell lymphoma and low grade B-cell lymphoproliferative disorder

Authors: Christopoulos, C.¹; Tassidou, A.²; Golfinopoulou, S.¹; Anastasiadis, G.³; Manetas, S.¹; Anagnostou, D.²

Source: Clinical & Laboratory Haematology, Volume 23, Number 2, April 2001 , pp. 139-142(4)

Buy & download fulltext article:

Price: $48.00 plus tax (Refund Policy)

Abstract:

The presence of a rearranged immunoglobulin gene, in addition to the expected T-cell receptor gene rearrangement, is a frequent, albeit poorly understood, finding in the setting of angioimmunoblastic lymphadenopathy. A case of an angioimmunoblastic T-cell lymphoma is presented, where this apparently paradoxical dual gene rearrangement could be ascribed to the coexistence of an occult B-cell lymphoproliferative disorder.

Keywords: Angioimmunoblastic lymphoma; angioimmunoblastic lymphadenopathy; discordant lymphoma; T-cell receptor gene rearrangement; immunoglobulin gene rearrangement

Document Type: Research article

DOI: http://dx.doi.org/10.1046/j.1365-2257.2001.00384.x

Affiliations: 1: Second Department of Internal Medicine, Thriasio General Hospital, Athens, Greece 2: Department of Haematopathology, Evangelismos General Hospital, Athens, Greece 3: Department of Dermatology, Thriasio General Hospital, Athens, Greece

Publication date: 2001-04-01